Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | CDC42 | P60953 | 1/20 | 0.32 |
| ▸ | RAC1 | P63000 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715525 | 0.84 | AKR1C3 (0.33) | AKR1C3AKR1C2PTGS1AKR1C1TP53 | |
| SCHEMBL7716181 | 0.80 | TP53 (0.36) | TP53MAPTSLC2A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7716185 | 0.80 | TP53 (0.33) | AKR1C3AKR1C2PTGS1AKR1C1TP53 | |
| SCHEMBL7716171 | 0.80 | TP53 (0.36) | TP53MAPTSLC2A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7105520 | 0.78 | F7 (0.36) | TP53MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL7714235 | 0.77 | MAPT (0.36) | TP53MAPTCYP1A2TSHRALDH1A1 | |
| SCHEMBL7714210 | 0.73 | ITGB1 (0.42) | — | |
| SCHEMBL7714207 | 0.73 | ITGB1 (0.42) | — | |
| SCHEMBL7260147 | 0.71 | RAB9A (0.36) | TP53MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7714205 | 0.71 | ITGB1 (0.58) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |