Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 3/20 | 0.30 |
| ▸ | RXRG | P48443 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL8519992 | 0.79 | TDP1 (0.37) | TDP1NR1H4RXRASLC22A6SLC22A8 | |
| SCHEMBL9769607 | 0.79 | NPSR1 (0.38) | TDP1NR1H4RXRAAKT1RARG | |
| SCHEMBL725191 | 0.79 | TDP1 (0.51) | TDP1NR1H4RXRASLC22A6SLC22A8 | |
| SCHEMBL9769638 | 0.75 | SNCA (0.39) | TDP1NR1H4AKT1MEN1MAPT | |
| SCHEMBL2340250 | 0.73 | TSHR (0.37) | TDP1AKT1MAPT | |
| Maleic Acid SCHEMBL11066791 | 0.71 | AKT1 (0.36) | TDP1AKT1MAPT | |
| SCHEMBL9769680 | 0.71 | NR1H4 (0.39) | TDP1NR1H4RXRAHSP90AA1HSP90AB1 | |
| SCHEMBL868580 | 0.69 | AKT1 (0.36) | TDP1RXRAAKT1PPARGMAPT | |
| Vinyl Chloride SCHEMBL726686 | 0.69 | AKT1 (0.34) | TDP1AKT1 | |
| Methacrylic Acid SCHEMBL7610614 | 0.68 | AKT1 (0.35) | TDP1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306374-B1 | READILY APPLICABLE TO THE NAIL, DRIES RAPIDLY AND LEAVES A PROTECTIVE FILM ON THE NAIL; COSMETICS | L'OREAL (FR) | 2001-10-23 | — | — | US | claimed |
| US-20020142017-A1 | Suspension of nanospheres of lipophilic active principle stabilized with water-dispersible polymers | L'OREAL (FR) | 2002-10-03 | — | — | US | disclosed |
| US-6306374-B1 | READILY APPLICABLE TO THE NAIL, DRIES RAPIDLY AND LEAVES A PROTECTIVE FILM ON THE NAIL; COSMETICS | L'OREAL (FR) | 2001-10-23 | — | — | US | disclosed |
| US-5753215-A | Cosmetic composition containing a pseudo-latex having remanence properties | L'OREAL (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5709850-A | PSEUDOLATEX CONTAINING NEUTRALIZED CARBOXYLIC POLYMER, PLASTICIZER | L'OREAL (FR) | 1998-01-20 | — | — | US | disclosed |
| US-5683681-A | CARBOXCYLIC ACID ADDITION POLYMER, PLASTICIZER | L'OREAL (FR) | 1997-11-04 | — | — | US | disclosed |
| US-5660820-A | INCLUDES PARTICLES OF A FILM-FORMING POLYMER CONTAINING CARBOXYLIC ACID FUNCTIONS NEUTRALIZED USING A NONVOLATILE MONOBASIC AGENT; PLASTICIZERS | L'OREAL (FR) | 1997-08-26 | — | — | US | disclosed |
| US-5620693-A | MIXTURE OF AQUEOUS DISPERSION OF PARTICLES OF FILM FORMING POLYMER HAVING PARTIALLY NEUTRALIZED CARBOXYLIC ACID FUNCTIONAL GROUPS, WAX HAVING SPECIFIED MELTING POINT; ENHANCED LENGTHENING AND CURVATURE ON EYELASHES | L'OREAL (FR) | 1997-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142017-A1 | Suspension of nanospheres of lipophilic active principle stabilized with water-dispersible polymers | LIPA, S100P, LSS | TDP1 1215/4885NR1H4 2985/4885RXRA 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.