Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725191 | 0.81 | TDP1 (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Crotonic Acid SCHEMBL158533 | 0.72 | TSHR (0.33) | TDP1ALDH1A1HSD17B10 | |
| Crotonic Acid SCHEMBL27531096 | 0.72 | TSHR (0.33) | TDP1ALDH1A1HSD17B10 | |
| Crotonic Acid SCHEMBL11318968 | 0.72 | TSHR (0.33) | TDP1ALDH1A1HSD17B10 | |
| Crotonic Acid SCHEMBL158532 | 0.72 | TSHR (0.33) | TDP1ALDH1A1HSD17B10 | |
| Crotonic Acid SCHEMBL11864311 | 0.72 | TSHR (0.33) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL7617402 | 0.72 | RXRA (0.37) | TDP1CYP2C19NR1H4RXRARXRB | |
| Crotonic Acid SCHEMBL15350522 | 0.71 | TNF (0.45) | TDP1ALDH1A1NR1H4RXRARXRB | |
| Crotonic Acid SCHEMBL15350519 | 0.71 | TNF (0.45) | TDP1ALDH1A1NR1H4RXRARXRB | |
| SCHEMBL5348982 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955003-A | Water-in-oil emulsion, composition containing the emulsion and use thereof | L'OREAL (FR) | 1999-09-21 | — | — | US | claimed |