SCHEMBL725191

SCHEMBL725191

C=Cc1cc(C(C)(C)C)ccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.51
RXRB P28702 3/20 0.44
NR1H4 Q96RI1 4/20 0.42
AKR1C2 P52895 3/20 0.41
AKR1C1 Q04828 1/20 0.41
SRD5A2 P31213 1/20 0.41
AKR1C3 P42330 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
EPHX2 P34913 1/20 0.40
NOTUM Q6P988 1/20 0.39
SERPINE1 P05121 1/20 0.38
RXRA P19793 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
RXRG P48443 1/20 0.38
RARB P10826 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22265173 0.83 ALDH1A1 (0.57) RXRBSRD5A2RXRAALDH1A1HPGD
Crotonic Acid SCHEMBL8519992 0.81 TDP1 (0.37) TDP1RXRBNR1H4AKR1C2AKR1C1
SCHEMBL5166078 0.79 NR1H4 (0.44) TDP1RXRBNR1H4EPHX2RXRA
SCHEMBL1813021 0.78 AKR1C2 (0.43) TDP1RXRBNR1H4AKR1C2AKR1C1
SCHEMBL1356449 0.77 TDP1 (0.71) TDP1RXRBNR1H4AKR1C2AKR1C1
SCHEMBL31528338 0.77 TDP1 (0.71) TDP1RXRBNR1H4AKR1C2AKR1C1
SCHEMBL18903931 0.77 MAPT (0.41) TDP1MAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL5962029 0.77 CSNK2A1 (0.50) SLC22A6SLC22A8SMN1; SMN2NOTUMALDH1A1
SCHEMBL4631399 0.76 TDP1 (0.59) TDP1RXRBNR1H4AKR1C2AKR1C1
SCHEMBL28506952 0.76 TDP1 (0.69) TDP1RXRBNR1H4AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3813780-B1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AT LEAST ONE COPOLYMER DERIVED FROM THE POLYMERIZATION OF AT LEAST ONE CROTONIC ACID MONOMER AND OF AT LEAST ONE VINYL ESTER MONOMER AND A FATTY AMINE OREAL (FR) 2025-12-24 EP claimed
EP-3621697-B1 DYE COMPOSITION BASED ON COPOLYMERS DERIVED FROM THE POLYMERIZATION OF AT LEAST ONE CROTONIC ACID MONOMER OR CROTONIC ACID DERIVATIVE AND OF AT LEAST ONE VINYL ESTER MONOMER AND ON SILICONE, AND PROCESS FOR DYEING KERATIN FIBERS USING THE SAME OREAL (FR) 2022-12-07 EP claimed
EP-3645123-B1 DYE COMPOSITION BASED ON COPOLYMERS DERIVED FROM THE POLYMERIZATION OF AT LEAST ONE CROTONIC ACID MONOMER OR CROTONIC ACID DERIVATIVE AND ON SILICONE OREAL (FR) 2021-07-21 EP claimed
EP-3621698-B1 DYE COMPOSITION BASED ON COPOLYMERS DERIVED FROM THE POLYMERIZATION OF AT LEAST ONE CROTONIC ACID MONOMER OR CROTONIC ACID DERIVATIVE AND OF AT LEAST ONE THICKENING POLYMER BEARING (METH)ACRYLIC ACID UNIT(S), AND PROCESS FOR DYEING KERATIN FIBERS USING SAME OREAL (FR) 2021-02-24 EP claimed
EP-3176187-B1 FORMALDEHYDE-FREE THERMALLY CURABLE POLYMERS ORGANIK KIMYA SANAYI VE TIC A S (TR) 2019-08-07 EP claimed
EP-1902077-B2 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2018-07-18 EP claimed
EP-3119821-B1 SECONDARY SUSPENDING AGENT FOR SUSPENSION POLYMERISATION REACTION SYNTHOMER UK LTD (GB) 2018-07-11 EP claimed
EP-1966253-B1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2015-08-12 EP claimed
EP-2676976-B1 Emulsion Polymers With Improved Wet Scrub Resistance Having One Or More Silicon Containing Compounds CELANESE EMULSIONS GMBH (DE) 2014-12-31 EP claimed
EP-1845415-B1 Process for producing an image using a first minimum bottom antireflective coating composition AZ ELECTRONIC MATERIALS USA (US) 2014-04-30 EP claimed
EP-1902077-B1 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2011-11-16 EP claimed
WO-2011133072-A1 ARRANGEMENT FOR OPERATING A HYDRAULIC DEVICE PARKER HANNIFIN AB (SE) 2011-10-27 WO claimed
EP-1784435-B1 METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS NUPLEX RESINS BV (NL) 2009-11-11 EP claimed
EP-1465877-B1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA (US) 2008-09-24 EP claimed
EP-1440097-B1 HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS RODENSTOCK GMBH (DE) 2008-03-12 EP claimed
EP-1466216-B1 PROCESS FOR PRODUCING AN IMAGE USING A FIRST MINIMUM BOTTOM ANTIREFLECTIVE COATING COMPOSITION AZ ELECTRONIC MATERIALS USA (US) 2006-07-26 EP claimed
EP-0284868-B1 Photoresist compositions MICROSI INC (US) 1995-05-03 EP claimed
EP-0222157-B1 RESIN COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-12-30 EP claimed
US-12606654-B2 Fluoropolymer production method and fluoropolymer DAIKIN INDUSTRIES, LTD. (JP) 2026-04-21 US disclosed
EP-0284868-A2 Photoresist compositions MicroSi, Inc. (a Delaware corporation) (US) 1988-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606654-B2 Fluoropolymer production method and fluoropolymer CBR1, CBR3, CCR4 TDP1 1607/4885RXRB 318/4885NR1H4 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.