Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328399 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2KMT2APLA2G4BMAPTPOLB | |
| SCHEMBL11276134 | 0.80 | FFAR1 (0.54) | SMN1; SMN2KMT2AMAPTPOLBNPC1 | |
| SCHEMBL864988 | 0.80 | APP (0.65) | SMN1; SMN2KMT2APLA2G4BMEN1MAPT | |
| SCHEMBL11281059 | 0.78 | NPC1 (0.55) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL11235640 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL1444267 | 0.77 | GAA (0.61) | SMN1; SMN2MAPTPOLBGAALMNA | |
| SCHEMBL23295 | 0.76 | PTGS2 (0.53) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL3732372 | 0.76 | ALDH1A1 (0.59) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL10399769 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2KMT2AMAPTPOLBGAA | |
| SCHEMBL20175325 | 0.76 | PLA2G4B (0.56) | SMN1; SMN2KMT2APLA2G4BMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | claimed |
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | disclosed |