Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718225 | 0.82 | ELANE (0.60) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7715931 | 0.81 | ELANE (0.55) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7710271 | 0.80 | MAPT (0.66) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7716159 | 0.78 | ELANE (0.59) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7715419 | 0.77 | KDM4E (0.81) | MAPTKDM4EMEN1KMT2AELANE | |
| SCHEMBL7710318 | 0.76 | TUBB4A (0.54) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7715411 | 0.75 | ELANE (0.52) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7710279 | 0.75 | KDM4E (0.62) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL17179315 | 0.72 | TUBB4A (0.63) | MAPTKDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL627038 | 0.70 | MEN1 (0.74) | MAPTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376670-B1 | BACTERICIDE FOR GRAMPOSITIVE BACTERIA | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| US-6103905-A | EFFECTIVE AGAINST DRUG RESISTANT GRAMPOSITIVE BACTERIAL INFECTIONS; ANTIBIOTICS | SEPRACOR, INC. (US) | 2000-08-15 | — | — | US | disclosed |
| WO-2000034265-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS | SEPRACOR, INC. (US) | 2000-06-15 | — | — | WO | disclosed |