Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718225 | 0.87 | ELANE (0.60) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7715931 | 0.86 | ELANE (0.55) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7715411 | 0.82 | ELANE (0.52) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7710318 | 0.80 | TUBB4A (0.54) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17179315 | 0.79 | TUBB4A (0.63) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7716152 | 0.78 | MAPT (0.55) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7715419 | 0.76 | KDM4E (0.81) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4270886 | 0.75 | ACHE (0.58) | ALDH1A1SMN1; SMN2LMNACYP2C9KDM4E | |
| SCHEMBL17179411 | 0.74 | AR (0.60) | ELANEMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7713938 | 0.74 | AR (0.64) | MAPTALDH1A1SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376670-B1 | BACTERICIDE FOR GRAMPOSITIVE BACTERIA | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| US-6103905-A | EFFECTIVE AGAINST DRUG RESISTANT GRAMPOSITIVE BACTERIAL INFECTIONS; ANTIBIOTICS | SEPRACOR, INC. (US) | 2000-08-15 | — | — | US | disclosed |