SCHEMBL7716168

SCHEMBL7716168

CC(C)C(C)(C)[SiH2]OCCCOc1cc[c]cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
SLC2A1 P11166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7716034 0.92 TDP1 (0.33) TDP1
SCHEMBL7719269 0.75
SCHEMBL7721185 0.74
SCHEMBL1244396 0.73 TDP1 (0.48) TDP1
SCHEMBL920141 0.71 TDP1 (0.60) TDP1
SCHEMBL10608344 0.70 RARB (0.50) TDP1SLC2A1
SCHEMBL2458265 0.70 TDP1 (0.39) TDP1
SCHEMBL10406354 0.69 TDP1 (0.39) TDP1SLC2A1
SCHEMBL3038199 0.69 TDP1 (0.41) TDP1SLC2A1
SCHEMBL23093206 0.69 ADRB2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391916-B1 ANTITUMOR AGENTS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2002-05-21 US claimed
US-6391916-B1 ANTITUMOR AGENTS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2002-05-21 US disclosed