Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716180 | 0.90 | DGAT1 (0.34) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7716470 | 0.81 | MAPT (0.34) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7716169 | 0.79 | ELANE (0.40) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7716179 | 0.79 | ELANE (0.40) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7714235 | 0.78 | MAPT (0.36) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7716183 | 0.78 | MAPT (0.37) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7105520 | 0.77 | F7 (0.36) | MAPTMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7258056 | 0.74 | ITGB1 (0.43) | — | |
| SCHEMBL7259945 | 0.74 | ITGB1 (0.47) | — | |
| SCHEMBL7259939 | 0.74 | ITGB1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |