Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716173 | 0.90 | MAPT (0.37) | GAAMAPTTP53MEN1NPY1R | |
| SCHEMBL7718437 | 0.82 | ADRA2A (0.33) | DGAT1CSGALNACT1GAAMAPTMAPKAPK2 | |
| SCHEMBL7716175 | 0.80 | P2RX3 (0.36) | GAAMAPTTP53P2RX3MEN1 | |
| SCHEMBL7716184 | 0.78 | MAPT (0.35) | MAPTTP53P2RX3MEN1KMT2A | |
| SCHEMBL7716187 | 0.78 | MAPT (0.35) | MAPTTP53P2RX3MEN1KMT2A | |
| SCHEMBL7716201 | 0.75 | ITGB1 (0.43) | — | |
| SCHEMBL7716196 | 0.75 | ITGB1 (0.43) | — | |
| SCHEMBL7710690 | 0.74 | ATM (0.39) | MAPTTP53 | |
| SCHEMBL7710729 | 0.74 | SLC2A1 (0.36) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7716457 | 0.73 | PAK4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |