Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.68 |
| ▸ | MTOR | P42345 | 8/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.43 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.43 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562390 | 0.87 | FAAH (0.64) | FAAHMTORPIK3CARPTORMLST8 | |
| SCHEMBL14574615 | 0.82 | FAAH (0.80) | FAAHKCNH2 | |
| SCHEMBL7715793 | 0.82 | FAAH (1.00) | FAAHKCNH2 | |
| SCHEMBL7710905 | 0.81 | FAAH (0.70) | FAAHKCNH2 | |
| SCHEMBL14574635 | 0.80 | FAAH (0.69) | FAAHKCNH2 | |
| SCHEMBL14574561 | 0.80 | FAAH (0.69) | FAAHKCNH2 | |
| SCHEMBL7711287 | 0.80 | FAAH (0.80) | FAAHKCNH2 | |
| SCHEMBL7715785 | 0.80 | FAAH (0.74) | FAAHMTORPIK3CAKCNH2 | |
| SCHEMBL14574600 | 0.80 | FAAH (0.68) | FAAHMTORPIK3CASYKKCNH2 | |
| SCHEMBL14574833 | 0.80 | FAAH (0.68) | FAAHMTORPIK3CARPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011126960-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2011-10-13 | — | — | WO | disclosed |