Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002557 | 0.94 | FAAH (0.70) | FAAHKCNH2 | |
| SCHEMBL1002009 | 0.93 | FAAH (0.68) | FAAHKCNH2 | |
| SCHEMBL7710905 | 0.90 | FAAH (0.70) | FAAHKCNH2 | |
| SCHEMBL14574635 | 0.89 | FAAH (0.69) | FAAHKCNH2 | |
| SCHEMBL14574561 | 0.89 | FAAH (0.69) | FAAHKCNH2 | |
| SCHEMBL14574615 | 0.89 | FAAH (0.80) | FAAHKCNH2 | |
| SCHEMBL7715793 | 0.89 | FAAH (1.00) | FAAHKCNH2 | |
| SCHEMBL14574555 | 0.88 | FAAH (0.67) | FAAHKCNH2 | |
| SCHEMBL14574598 | 0.85 | FAAH (0.63) | FAAHKCNH2 | |
| SCHEMBL7717931 | 0.84 | FAAH (0.80) | FAAHKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2555772-B1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME (US) | 2017-01-11 | — | — | EP | disclosed |
| EP-2555772-B1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME (US) | 2017-01-11 | — | — | EP | disclosed |
| US-9193697-B2 | Oxazole derivatives useful as modulators of FAAH | MERCK SHARP & DOHME CORP. (US) | 2015-11-24 | — | — | US | disclosed |
| US-9193697-B2 | Oxazole derivatives useful as modulators of FAAH | MERCK SHARP & DOHME CORP. (US) | 2015-11-24 | — | — | US | disclosed |
| US-9193697-B2 | Oxazole derivatives useful as modulators of FAAH | MERCK SHARP & DOHME CORP. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20130018048-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | US | disclosed |
| US-20130018048-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | US | disclosed |
| US-20130018048-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | US | disclosed |
| WO-2011126960-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018048-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | FAAH, FAAH2, ALOX5 | FAAH 1/4885KCNH2 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.