Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267395 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL6036872 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL3552039 | 0.77 | CA1 (0.50) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL7716260 | 0.77 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20676030 | 0.76 | POLB (0.58) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL6268227 | 0.75 | CA1 (0.65) | KMT2ACA1CA2ALDH1A1MAPT | |
| SCHEMBL6270269 | 0.75 | NR4A2 (0.48) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL592406 | 0.73 | CA1 (0.68) | POLBCA1CA2ALDH1A1MAPT | |
| SCHEMBL2645555 | 0.72 | PDE5A (0.46) | MAPT | |
| SCHEMBL28529289 | 0.72 | POLB (0.42) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391597-B1 | GENERATING PREFERENTIAL CARBOXYLIC ACID COMPOUND; OBTAIN PREFERENTIAL ESTER, INCUBATE HYDROLASE, RECOVER PREFERENTIAL COMPOUND | NAGASE & COMPANY, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |