Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718441 | 0.91 | ADRA2A (0.33) | MAPTP2RX3MEN1KMT2A | |
| SCHEMBL7710720 | 0.83 | ITGB1 (0.42) | — | |
| SCHEMBL7710717 | 0.83 | ITGB1 (0.42) | — | |
| SCHEMBL7710712 | 0.83 | ITGB1 (0.42) | — | |
| SCHEMBL7716460 | 0.80 | ITGB1 (0.35) | P2RX3 | |
| SCHEMBL7716161 | 0.79 | MAPT (0.36) | MAPTNPY5RNPC1SMN1; SMN2MEN1 | |
| SCHEMBL7716457 | 0.78 | PAK4 (0.31) | MDM2PAK4 | |
| SCHEMBL7710734 | 0.77 | SLC2A1 (0.41) | MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7264638 | 0.75 | P2RX7 (0.30) | — | |
| SCHEMBL7716156 | 0.74 | ITGB1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |