Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.53 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045991 | 0.80 | SMN1; SMN2 (0.58) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10952972 | 0.76 | KMT2A (0.51) | KMT2AHPGDMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL15979655 | 0.76 | NAMPT (0.44) | KMT2AHPGDMEN1SMN1; SMN2MAPT | |
| SCHEMBL509681 | 0.76 | NAMPT (0.42) | KMT2AHPGDMEN1SMN1; SMN2MAPT | |
| SCHEMBL12094827 | 0.74 | NAMPT (0.43) | KMT2AHPGDMEN1SMN1; SMN2MAPT | |
| SCHEMBL1983161 | 0.74 | NAMPT (0.41) | KMT2AHPGDMEN1SMN1; SMN2MAPT | |
| SCHEMBL28605586 | 0.73 | CYP2D6 (0.45) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14583507 | 0.73 | NAMPT (0.74) | SMN1; SMN2MAPTKDM4ENPC1RAB9A | |
| SCHEMBL13319132 | 0.73 | PLOD2 (0.46) | KMT2AHPGDMEN1SMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL28462129 | 0.73 | KMT2A (0.90) | KMT2AHPGDMEN1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6392089-B1 | DEBLOCKING USING RADIATION | UNIVERSITY OF MARYLAND | 2002-05-21 | — | — | US | disclosed |