SCHEMBL10952972

SCHEMBL10952972

Cn1ccnc1CC(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 2/20 0.51
USP1 O94782 1/20 0.45
CTNNB1 P35222 1/20 0.44
WNT3A P56704 1/20 0.44
HTR1A P08908 2/20 0.43
ALDH1A1 P00352 6/20 0.43
RAB9A P51151 5/20 0.43
NPC1 O15118 4/20 0.43
HPGD P15428 2/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 2/20 0.43
TP53 P04637 1/20 0.43
ALOX12 P18054 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2D6 P10635 2/20 0.42
PLOD2 O00469 1/20 0.42
PLOD3 O60568 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9702232 0.84 RAB9A (0.50) KMT2AMEN1USP1HTR1AALDH1A1
Benzoic Acid SCHEMBL2518954 0.79 KMT2A (0.50) KMT2AMEN1ALDH1A1RAB9AHPGD
SCHEMBL5722028 0.79 ALPG (0.50) RAB9APOLBTP53SMN1; SMN2FDPS
SCHEMBL2137686 0.79 FDPS (0.49) KMT2AMEN1ALDH1A1NPC1HPGD
Iodide SCHEMBL10528563 0.79 RAB9A (0.65) KMT2AMEN1ALDH1A1RAB9ANPC1
SCHEMBL4412889 0.78 NPC1 (0.45) KMT2AMEN1ALDH1A1RAB9ANPC1
SCHEMBL7983149 0.78 KMT2A (0.46) KMT2AMEN1ALDH1A1RAB9ANPC1
Hydrochloric Acid SCHEMBL9715312 0.78 FDPS (0.47) KMT2AMEN1ALDH1A1NPC1HPGD
SCHEMBL4408950 0.77 HSP90AA1 (0.52) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL7716484 0.76 KMT2A (0.53) KMT2AMEN1CTNNB1WNT3AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4551447-A Beta-imidazolyl-alpha-(trifluoromethyl)ethenyl phosphates and insecticidal and miticidal use SHELL OIL COMPANY (US) 1985-11-05 US disclosed