Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362414 | 0.84 | DPP4 (0.61) | DPP4KDM4ELMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL3361903 | 0.83 | DPP4 (0.62) | DPP4KDM4ELMNAHSD17B10 | |
| SCHEMBL3361298 | 0.83 | DPP4 (0.46) | DPP4KDM4ELMNAHSD17B10MAPK1 | |
| SCHEMBL3361560 | 0.83 | DPP4 (0.74) | DPP4LMNA | |
| SCHEMBL21712161 | 0.76 | EGLN1 (0.45) | DPP4KDM4ELMNAHSD17B10MAPK1 | |
| SCHEMBL3363200 | 0.75 | DPP4 (0.55) | DPP4MAPK1 | |
| Hydrochloric Acid SCHEMBL3366022 | 0.74 | DPP4 (0.55) | DPP4MAPK1 | |
| SCHEMBL7716787 | 0.74 | DPP4 (1.00) | DPP4 | |
| SCHEMBL3363078 | 0.73 | DPP4 (0.58) | DPP4 | |
| SCHEMBL3363962 | 0.73 | DPP4 (0.60) | DPP4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |