Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361885 | 0.81 | DPP4 (0.67) | DPP4PDE10AALDH1A1POLBHPGD | |
| SCHEMBL3360594 | 0.80 | DPP4 (0.71) | DPP4 | |
| Hydrochloric Acid SCHEMBL3364779 | 0.80 | DPP4 (0.68) | DPP4PDE10AALDH1A1POLBHPGD | |
| SCHEMBL3361845 | 0.79 | DPP4 (1.00) | DPP4 | |
| SCHEMBL7716544 | 0.74 | DPP4 (0.65) | DPP4 | |
| SCHEMBL7720666 | 0.73 | DPP4 (0.61) | DPP4HPGD | |
| SCHEMBL3360544 | 0.73 | DPP4 (0.61) | DPP4PDE10A | |
| Hydrochloric Acid SCHEMBL3362783 | 0.72 | DPP4 (0.62) | DPP4HPGD | |
| Hydrochloric Acid SCHEMBL3369616 | 0.72 | DPP4 (0.62) | DPP4PDE10A | |
| SCHEMBL3361983 | 0.72 | DPP4 (0.56) | DPP4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |