Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 10/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711788 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL461294 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL7715678 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL2268958 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL7711854 | 0.73 | RAB9A (0.59) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL10631888 | 0.72 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL2270814 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL7711791 | 0.72 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL10630084 | 0.72 | TYMP (1.00) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL9840133 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |