Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | TYMP | P19971 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274936 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL8798438 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL7711854 | 0.70 | RAB9A (0.59) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL7716586 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL2270814 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL2267352 | 0.69 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL10630084 | 0.69 | TYMP (1.00) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL10631888 | 0.67 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL7711788 | 0.67 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL2274843 | 0.66 | ATM (0.40) | KDM4EALDH1A1HPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001984-A1 | PYRAZOLO(1,5-a)BENZIMIDAZOLE COUPLERS | EASTMAN KODAK COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |