Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.34 |
| ▸ | DRD3 | P35462 | 9/20 | 0.34 |
| ▸ | DRD4 | P21917 | 7/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 5/20 | 0.32 |
| ▸ | DRD5 | P21918 | 5/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22557845 | 0.81 | DRD2 (0.39) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL7720307 | 0.78 | DRD2 (0.35) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL7717808 | 0.75 | PTGIR (0.31) | — | |
| SCHEMBL7717824 | 0.74 | CA12 (0.38) | — | |
| SCHEMBL29398439 | 0.74 | DRD2 (0.41) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL22557831 | 0.74 | DRD2 (0.41) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL8078312 | 0.73 | DRD2 (0.33) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL22568962 | 0.72 | DRD2 (0.38) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL7487183 | 0.72 | ADRB2 (0.46) | — | |
| SCHEMBL7779651 | 0.70 | PTGIR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |