Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 8/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.55 |
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.55 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.55 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.55 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403823 | 0.87 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL11435906 | 0.86 | CXCL8 (0.71) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL3137707 | 0.84 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL12129515 | 0.84 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL3151521 | 0.84 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL6931840 | 0.84 | CXCL8 (0.69) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL13186033 | 0.81 | CXCL8 (0.68) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL10992714 | 0.79 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL2906103 | 0.79 | CXCL8 (0.65) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL10675998 | 0.78 | CXCL8 (0.67) | CXCL8PTGS2TTRPTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369260-B1 | ANTIAGGLOMERANTS AND ANTICOAGULANTS | LABORATORI ALCHEMICA S.R.L. (IT) | 2002-04-09 | — | — | US | disclosed |
| EP-1038534-A2 | Process for the preparation of a conjugate of pharmacologically active substances | LABORATORI ALCHEMIA S.R.L. (IT) | 2000-09-27 | — | — | EP | disclosed |
| EP-0793507-A2 | PROCESS FOR THE PREPARATION OF A PHARMACOLOGICALLY ACTIVE CHEMICAL COMBINATION | LABORATORI ALCHEMIA S.R.L. (IT) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996015809-A2 | PROCESS FOR THE PREPARATION OF A PHARMACOLOGICALLY ACTIVE CHEMICAL COMBINATION | LABORATORI ALCHEMIA S.R.L. (IT) | 1996-05-30 | — | — | WO | disclosed |