Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 8/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.52 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403823 | 0.84 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL7716835 | 0.84 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL11435906 | 0.83 | CXCL8 (0.71) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL3137707 | 0.82 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL12129515 | 0.82 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL3151521 | 0.82 | CXCL8 (1.00) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL13186033 | 0.78 | CXCL8 (0.68) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL753104 | 0.78 | MEN1 (0.59) | CXCL8CYP3A4KMT2AMEN1CYP1A2 | |
| SCHEMBL1159922 | 0.78 | MEN1 (0.59) | CXCL8CYP3A4KMT2AMEN1CYP1A2 | |
| SCHEMBL6322741 | 0.78 | MEN1 (0.59) | CXCL8CYP3A4KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082290-B1 | PROCESS FOR THE PREPARATION OF ACECLOFENAC | RUSSINSKY LTD (IE) | 2003-11-26 | — | — | EP | disclosed |
| US-20030060657-A1 | Process for the preparation of Aceclofenac | RUSSINSKY LIMITED | 2003-03-27 | — | — | US | disclosed |
| EP-1082290-A1 | PROCESS FOR THE PREPARATION OF ACECLOFENAC | RUSSINSKY LIMITED (IE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999055660-A1 | PROCESS FOR THE PREPARATION OF ACECLOFENAC | RUSSINSKY LIMITED (IE) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060657-A1 | Process for the preparation of Aceclofenac | AADAC, NAT1, CTRC | CXCL8 1700/4885PTGS2 179/4885TTR 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.