Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555109 | 0.93 | KDM4E (0.48) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| SCHEMBL7716908 | 0.93 | KDM4E (0.48) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| SCHEMBL2547933 | 0.93 | KDM4E (0.48) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2552428 | 0.92 | KDM4E (0.47) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2552429 | 0.92 | KDM4E (0.47) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| SCHEMBL2555154 | 0.88 | KDM4E (0.48) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| SCHEMBL2553885 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA | |
| SCHEMBL2551564 | 0.83 | HRH3 (0.45) | SMN1; SMN2ALDH1A1KCNH2HRH3FABP6 | |
| SCHEMBL2549964 | 0.83 | KCNH2 (0.49) | ALDH1A1LMNAHTTKCNH2HRH3 | |
| SCHEMBL2554540 | 0.82 | KDM4E (0.47) | SMN1; SMN2KDM4ERECQLALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121309-A1 | PHENYL SULFONYL DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-06 | — | — | WO | disclosed |