Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078970 | 0.89 | GAA (0.73) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL7783912 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL7715855 | 0.82 | MAPT (0.49) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL6816075 | 0.80 | KDM4E (0.68) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL7718022 | 0.77 | LMNA (0.73) | KDM4EGAAPOLBMEN1KMT2A | |
| SCHEMBL8575023 | 0.77 | NPSR1 (1.00) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL32685674 | 0.76 | GAA (0.71) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL3506164 | 0.75 | KDM4E (0.69) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL2079586 | 0.74 | NPSR1 (0.68) | KDM4EGAAMAPTNPSR1POLB | |
| SCHEMBL12174971 | 0.71 | NPSR1 (0.69) | KDM4EGAAMAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |