Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716936 | 0.82 | KDM4E (0.70) | MAPTKDM4EGAALMNANPSR1 | |
| SCHEMBL7783912 | 0.80 | KDM4E (0.53) | MAPTKDM4EGAALMNANPSR1 | |
| SCHEMBL6814769 | 0.76 | KDM4E (0.44) | MAPTKDM4EGAANPSR1MEN1 | |
| SCHEMBL7718022 | 0.73 | LMNA (0.73) | KDM4EGAALMNAMEN1KMT2A | |
| SCHEMBL6814819 | 0.73 | MAPT (0.46) | MAPTKDM4EGAALMNANPSR1 | |
| SCHEMBL7078970 | 0.71 | GAA (0.73) | MAPTKDM4EGAALMNANPSR1 | |
| SCHEMBL6816563 | 0.70 | POLB (0.65) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL6815952 | 0.68 | PPARG (0.43) | MAPTKDM4EGAANPSR1POLB | |
| SCHEMBL7717489 | 0.65 | ALDH1A1 (0.56) | MAPTKDM4EGAALMNAMEN1 | |
| SCHEMBL31149107 | 0.65 | MEN1 (0.47) | MAPTKDM4ELMNAIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |