SCHEMBL7716941

SCHEMBL7716941

CC(C)C1CCCC(=O)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
PTPN1 P18031 2/20 0.38
PTPRC P08575 1/20 0.38
PTPRF P10586 1/20 0.38
CDC25B P30305 1/20 0.38
HTT P42858 2/20 0.36
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18289353 0.90 PTPN1 (0.37) CYP2A6MAOAMAOBPTPN1PTPRC
SCHEMBL9880849 0.79 S100A4 (0.40) MAOBCDC25BALDH1A1HTR2CACHE
SCHEMBL14166580 0.77 CYP2A6 (0.46) CYP2A6MAOAMAOBALDH1A1BCHE
SCHEMBL7712806 0.77 CYP2A6 (0.46) CYP2A6MAOAMAOBBCHEACHE
SCHEMBL3296406 0.75 IDO1 (0.49) PRCP
SCHEMBL7708893 0.75 CYP2A6 (0.43) CYP2A6MAOAMAOBHTR2CBCHE
SCHEMBL11650002 0.74 XIAP (0.36) CYP2A6MAOAMAOBPTPN1PTPRC
SCHEMBL6422853 0.74 CYP2A6 (0.46) CYP2A6MAOAMAOBPTPN1PTPRC
SCHEMBL14167073 0.73 CYP2A6 (0.42) CYP2A6MAOAMAOBPTPN1HTR2C
Hydrochloric Acid SCHEMBL11654730 0.73 XIAP (0.37) CYP2A6MAOAMAOBPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6369110-B1 PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM SUMITOMO PHARMACEUTICALS COMPANY (JP) 2002-04-09 US disclosed
EP-1083166-A1 NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-03-14 EP disclosed