Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12238362 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| Ammonia Solution, Strong SCHEMBL27972911 | 0.98 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| Acetonitrile SCHEMBL28928718 | 0.89 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| SCHEMBL10886210 | 0.82 | RECQL (0.50) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| SCHEMBL23072800 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| SCHEMBL12354031 | 0.78 | CYP3A4 (0.45) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 | |
| SCHEMBL14305114 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNACES2CES1 | |
| SCHEMBL8151621 | 0.78 | NPC1 (0.36) | ALDH1A1ACHECYP2C19CYP1A2TSHR | |
| SCHEMBL20921261 | 0.78 | CA1 (0.52) | ALDH1A1CYP3A4RECQLTDP1ACHE | |
| SCHEMBL25665734 | 0.78 | CYP3A4 (0.45) | ALDH1A1CYP3A4CYP2C9RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046071-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SRL (BE) | 2025-03-06 | — | — | WO | claimed |
| CN-114460203-B | Method for simultaneously detecting methyl p-toluenesulfonate, ethyl p-toluenesulfonate and isopropyl p-toluenesulfonate in medicine | 浙江海正药业股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-114460203-A | Method for simultaneously detecting methyl p-toluenesulfinate, ethyl p-toluenesulfinate and isopropyl p-toluenesulfinate in medicine | 浙江海正药业股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-113461393-A | Dry-mixed self-leveling mortar | 龙南县彩艺装饰材料厂 | 2021-10-01 | — | — | CN | claimed |
| US-11053273-B2 | Process for the production of estetrol intermediates | ESTETRA S.P.R.L. (BE) | 2021-07-06 | — | — | US | claimed |
| EP-2714712-B1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SPRL (BE) | 2016-08-24 | — | — | EP | claimed |
| CN-103619867-B | For generation of the method for oestetrol intermediate | ESTETRA S.A. (BE) | 2015-12-23 | — | — | CN | claimed |
| US-20140107091-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA S.A. (BE) | 2014-04-17 | — | — | US | claimed |
| CN-103619867-A | Process for the production of estetrol intermediates | ESTETRA S A | 2014-03-05 | — | — | CN | claimed |
| WO-2012164095-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA S.A. (BE) | 2012-12-06 | — | — | WO | claimed |
| US-6380397-B1 | HALOGENATION AN OXOESTER COMPOUND; HYDROLYSIS AND DECARBOXYLATION; ALKYLATION; AMINATION; REACTING OXALY CHLORIDE | ELI LILLY AND COMPANY | 2002-04-30 | — | — | US | claimed |
| US-20250313592-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SRL (BE) | 2025-10-09 | — | — | US | disclosed |
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025046071-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SRL (BE) | 2025-03-06 | — | — | WO | disclosed |
| EP-4514816-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | Estetra SRL (BE) | 2025-03-05 | — | — | EP | disclosed |
| US-4717756-A | HYDROPEROXIDE INITIATOR, SULFUR REDUCTANT, HYDROGEN HALOGENIDE SALT, COPPER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-01-05 | — | — | US | disclosed |
| EP-0231395-A1 | PROCESS FOR PRODUCING METHACRYLATE POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-12 | — | — | EP | disclosed |
| EP-0217545-A1 | Method for the production of polymethacrylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |
| EP-0214815-A1 | Method for in-mold polymerization of unsaturated compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-18 | — | — | EP | disclosed |
| EP-0212980-A2 | Method for the production of polymethyl methacrylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053273-B2 | Process for the production of estetrol intermediates | SULT1A1, DHCR7, SULT1E1 | ALDH1A1 361/4885CYP3A4 6/4885CYP2C9 87/4885 |
| US-20250313592-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | SULT1A1, SRD5A2, SULT1E1 | ALDH1A1 155/4885CYP3A4 59/4885CYP2C9 106/4885 |
| US-20140107091-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | DHCR7, SULT1A1, SULT1E1 | ALDH1A1 449/4885CYP3A4 10/4885CYP2C9 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.