SCHEMBL7717344

SCHEMBL7717344

CCOC1=C/C(=C2/C=C(OCC)c3ccccc3C2=O)C(=O)c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.74
PTPRC P08575 3/20 0.74
PTPN1 P18031 2/20 0.46
CTDSP1 Q9GZU7 1/20 0.43
CDC25A P30304 2/20 0.42
IDO1 P14902 2/20 0.42
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NSD2 O96028 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RAB9A P51151 2/20 0.41
MAP2K7 O14733 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717346 1.00 CDC25B (0.74) CDC25BPTPRCPTPN1CTDSP1CDC25A
SCHEMBL5595641 0.85 PTPRC (1.00) CDC25BPTPRCPTPN1CTDSP1CDC25A
SCHEMBL11919736 0.83 PTPRC (0.54) CDC25BPTPRCPTPN1CTDSP1MAPT
SCHEMBL7718306 0.82 PTPRC (0.51) CDC25BPTPRCPTPN1ALDH1A1LMNA
SCHEMBL7718305 0.82 PTPRC (0.51) CDC25BPTPRCPTPN1ALDH1A1LMNA
SCHEMBL7719270 0.79 PTPN1 (0.71) CDC25BPTPRCPTPN1CDC25AIDO1
SCHEMBL29428188 0.79 PTPN1 (0.71) CDC25BPTPRCPTPN1CDC25AIDO1
SCHEMBL7719273 0.79 PTPN1 (0.71) CDC25BPTPRCPTPN1CDC25AIDO1
SCHEMBL2511730 0.78 CDC25B (0.74) CDC25BPTPRCPTPN1CTDSP1CDC25A
SCHEMBL29800450 0.78 CDC25B (0.74) CDC25BPTPRCPTPN1CTDSP1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208186-B2 Latex comprising colorant and methods of making the same XEROX CORPORATION (US) 2019-02-19 US claimed
US-8551188-B2 Composition comprising a hydrophobic dye, a particular organic and/or mineral alkaline agent, a particular compound (I) and a particular organic compound (II), and dyeing use thereof L'OREAL (FR) 2013-10-08 US claimed
US-20120204357-A1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF L'OREAL (FR) 2012-08-16 US claimed
US-6406685-B1 COSMETICS FOR HAIR AND SKIN WITHOUT BLEEDING L'OREAL USA (FR) 2002-06-18 US claimed
US-6333026-B1 MIXING-ALKOXY-(2,2'-BINAPHTHYLIDENE)-1,1'-DIONE DERIVATIVE WITH COSMETIC FORMULATION FOR LENGTHENING HOLD OF COSMETIC, DECREASING MIGRATION/TRANSFERRING, STREAKING L'OREAL (FR) 2001-12-25 US claimed
EP-1032353-B1 COSMETIC COMPOSITION COMPRISING A COMPOUND SUCH AS INDIGOID OREAL (FR) 2001-09-05 EP claimed
EP-1008338-A1 Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, to impart antimicrobial and long wearing properties L'OREAL (FR) 2000-06-14 EP claimed
EP-2473152-B1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING OREAL (FR) 2020-03-18 EP disclosed
US-8551188-B2 Composition comprising a hydrophobic dye, a particular organic and/or mineral alkaline agent, a particular compound (I) and a particular organic compound (II), and dyeing use thereof L'OREAL (FR) 2013-10-08 US disclosed
US-20120204357-A1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF L'OREAL (FR) 2012-08-16 US disclosed
US-6406685-B1 COSMETICS FOR HAIR AND SKIN WITHOUT BLEEDING L'OREAL USA (FR) 2002-06-18 US disclosed
US-6333026-B1 MIXING-ALKOXY-(2,2'-BINAPHTHYLIDENE)-1,1'-DIONE DERIVATIVE WITH COSMETIC FORMULATION FOR LENGTHENING HOLD OF COSMETIC, DECREASING MIGRATION/TRANSFERRING, STREAKING L'OREAL (FR) 2001-12-25 US disclosed
EP-1008338-A1 Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, to impart antimicrobial and long wearing properties L'OREAL (FR) 2000-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120204357-A1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF KRT18, DSG1, DSC1 CDC25B 3180/4885PTPRC 3603/4885PTPN1 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.