SCHEMBL7718306

SCHEMBL7718306

CCCCCCOC1=CC(=C2C=C(OCCCCCC)c3ccccc3C2=O)C(=O)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.51
CDC25B P30305 1/20 0.51
PTPN1 P18031 4/20 0.51
SOAT1 P35610 9/20 0.44
ALDH1A1 P00352 2/20 0.41
APAF1 O14727 1/20 0.41
PTPN11 Q06124 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
NPC1 O15118 1/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718305 1.00 PTPRC (0.51) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL5595620 0.88 PTPRC (0.69) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL5595746 0.88 PTPRC (0.69) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL4294847 0.86 PTPRC (0.71) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL11919737 0.85 PTPN1 (0.40) PTPRCCDC25BPTPN1SOAT1PTPN11
Naphthoquinone SCHEMBL8525306 0.82 PTPRC (0.61) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL7717344 0.82 CDC25B (0.74) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL7717346 0.82 CDC25B (0.74) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL9713908 0.81 CDC25B (0.56) PTPRCCDC25BPTPN1SOAT1ALDH1A1
SCHEMBL9628579 0.81 CDC25B (0.56) PTPRCCDC25BPTPN1SOAT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6406685-B1 COSMETICS FOR HAIR AND SKIN WITHOUT BLEEDING L'OREAL USA (FR) 2002-06-18 US claimed
EP-1032353-B1 COSMETIC COMPOSITION COMPRISING A COMPOUND SUCH AS INDIGOID OREAL (FR) 2001-09-05 EP claimed
EP-1008338-A1 Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, to impart antimicrobial and long wearing properties L'OREAL (FR) 2000-06-14 EP claimed
US-6406685-B1 COSMETICS FOR HAIR AND SKIN WITHOUT BLEEDING L'OREAL USA (FR) 2002-06-18 US disclosed
US-6333026-B1 MIXING-ALKOXY-(2,2'-BINAPHTHYLIDENE)-1,1'-DIONE DERIVATIVE WITH COSMETIC FORMULATION FOR LENGTHENING HOLD OF COSMETIC, DECREASING MIGRATION/TRANSFERRING, STREAKING L'OREAL (FR) 2001-12-25 US disclosed
EP-1032353-B1 COSMETIC COMPOSITION COMPRISING A COMPOUND SUCH AS INDIGOID OREAL (FR) 2001-09-05 EP disclosed
EP-1008338-A1 Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, to impart antimicrobial and long wearing properties L'OREAL (FR) 2000-06-14 EP disclosed