Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159312 | 0.82 | ALDH1A1 (0.35) | CHRNA7CHRNA10CHRNA9AHRMAOB | |
| SCHEMBL8943845 | 0.79 | NR5A1 (0.49) | TSHRLTA4H | |
| SCHEMBL7717146 | 0.79 | RELA (0.48) | — | |
| SCHEMBL7717149 | 0.79 | RELA (0.48) | — | |
| SCHEMBL16922630 | 0.77 | AHR (0.43) | CHRNA7CHRNA10CHRNA9AHRMAOB | |
| SCHEMBL7716044 | 0.76 | RELA (0.48) | MAOBMAOAACHE | |
| SCHEMBL13372121 | 0.76 | RELA (0.48) | MAOBMAOAACHE | |
| SCHEMBL10128949 | 0.76 | RELA (0.48) | MAOBMAOAACHE | |
| SCHEMBL7717148 | 0.76 | RELA (0.48) | MAOBMAOAACHE | |
| SCHEMBL13358227 | 0.76 | RELA (0.48) | MAOBMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20020185634-A1 | Two-photon or higher-order absorbing optical materials and methods of use | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-12 | — | — | US | disclosed |
| US-6267913-B1 | IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2001-07-31 | — | — | US | disclosed |