Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 9/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717403 | 0.84 | HDAC8 (0.38) | HDAC8APPPTPN11CDC25BAHR | |
| SCHEMBL7717152 | 0.81 | CYP19A1 (0.43) | ALDH1A1MAPT | |
| SCHEMBL7717151 | 0.79 | NPSR1 (0.41) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL7716047 | 0.79 | NPSR1 (0.41) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL7717396 | 0.76 | CHRNA7 (0.38) | AHR | |
| SCHEMBL7717703 | 0.70 | NR4A1 (0.41) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL7877481 | 0.70 | TDP1 (0.44) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL130522 | 0.69 | NPSR1 (0.46) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL7719724 | 0.68 | CHRM3 (0.38) | MEN1ALDH1A1LMNAPLA2G1BKMT2A | |
| SCHEMBL17246941 | 0.68 | NPSR1 (0.56) | MEN1ALDH1A1LMNAPLA2G1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20020185634-A1 | Two-photon or higher-order absorbing optical materials and methods of use | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-12 | — | — | US | disclosed |
| US-6267913-B1 | IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2001-07-31 | — | — | US | disclosed |