Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 9/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717399 | 0.84 | HDAC8 (0.37) | HDAC8PTPN11APPCDC25BAHR | |
| SCHEMBL7717153 | 0.80 | CYP19A1 (0.41) | CNR1 | |
| SCHEMBL7716050 | 0.78 | CNR1 (0.49) | CNR1NR1H4 | |
| SCHEMBL7717154 | 0.78 | CNR1 (0.49) | CNR1NR1H4 | |
| SCHEMBL7717396 | 0.71 | CHRNA7 (0.38) | AHR | |
| SCHEMBL15800664 | 0.69 | TSHR (0.51) | PTPN11NR1H4 | |
| SCHEMBL5843455 | 0.69 | CNR1 (0.47) | CNR1NR1H4 | |
| SCHEMBL7717705 | 0.69 | CNR1 (0.50) | APPCNR1NR1H4 | |
| SCHEMBL130523 | 0.68 | CNR1 (0.54) | CNR1NR1H4 | |
| SCHEMBL30232756 | 0.68 | CNR1 (0.54) | CNR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20020185634-A1 | Two-photon or higher-order absorbing optical materials and methods of use | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-12 | — | — | US | disclosed |
| US-6267913-B1 | IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2001-07-31 | — | — | US | disclosed |