Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717539 | 1.00 | SIRT2 (0.35) | SIRT2MMP1MMP2MMP9ADAM17 | |
| SCHEMBL7718984 | 0.82 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7718980 | 0.82 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7717495 | 0.81 | SIRT2 (0.36) | SIRT2 | |
| SCHEMBL7717491 | 0.81 | SIRT2 (0.36) | SIRT2 | |
| SCHEMBL7714044 | 0.79 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714045 | 0.79 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7169453 | 0.79 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714912 | 0.76 | — | — | |
| SCHEMBL7719423 | 0.76 | FNTA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |