Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718727 | 0.91 | THRB (0.41) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL7717673 | 0.89 | KDM4E (0.50) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL8432616 | 0.81 | ENPP2 (0.45) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL7712999 | 0.80 | THRB (0.44) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL9749730 | 0.78 | THRB (0.41) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL13743964 | 0.77 | BRD4 (0.44) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL14388913 | 0.77 | THRB (0.39) | THRBPTGS2PTGS1PHLPP2MEN1 | |
| SCHEMBL14388748 | 0.76 | THRB (0.62) | THRBPHLPP2MEN1ALDH1A1MAPT | |
| SCHEMBL14388838 | 0.76 | THRB (0.62) | THRBPHLPP2MEN1ALDH1A1MAPT | |
| SCHEMBL14388756 | 0.75 | THRB (0.36) | THRBPTGS2PTGS1PHLPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| US-5686642-A | Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |
| US-5597902-A | MONOAZO DYES, DISAZO DYES, NAPHTHOL DYES AND TRIAZO DYES FOR SILK, WOOL, LEATHER AND POLYAMIDES OR CELLULOSE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5093484-A | Water soluble; colorfast shades on cotton | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |