Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719701 | 0.96 | FGFR1 (0.52) | PDE10ACYP1A2FGFR1HPGDSMN1; SMN2 | |
| SCHEMBL7714523 | 0.93 | PDE10A (0.48) | PDE10ACYP1A2FGFR1DRD2DRD3 | |
| SCHEMBL7718954 | 0.91 | PDE10A (0.48) | PDE10ACYP1A2FGFR1DRD2DRD3 | |
| SCHEMBL7714451 | 0.90 | PDE2A (0.43) | PDE10ACYP1A2FGFR1DRD2DRD3 | |
| SCHEMBL2331041 | 0.88 | FGFR1 (0.53) | PDE10ACYP1A2FGFR1ALDH1A1ESR1 | |
| SCHEMBL7719698 | 0.88 | PDE2A (0.42) | PDE10ACYP1A2FGFR1DRD2DRD3 | |
| SCHEMBL2327085 | 0.87 | FGFR1 (0.54) | PDE10ACYP1A2FGFR1ALDH1A1ESR1 | |
| SCHEMBL2327812 | 0.86 | ACSS2 (0.50) | PDE10ACYP1A2FGFR1ALDH1A1ESR1 | |
| SCHEMBL2328549 | 0.85 | ACSS2 (0.50) | PDE10ACYP1A2FGFR1HPGDSMN1; SMN2 | |
| SCHEMBL2323904 | 0.85 | PPARA (0.48) | PDE10ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246808-A1 | 1,2-DIARYL BENZIMIDAZOLES FOR TREATING ILLNESSES ASSOCIATED WITH A MICROGLIA ACTIVATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051473-A1 | 1,2-DIARYL BENZIMIDAZOLES FOR TREATING ILLNESSES ASSOCIATED WITH A MICROGLIA ACTIVATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | disclosed |