Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CBFB | Q13951 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.54 |
| ▸ | PDE5A | O76074 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563722 | 0.89 | PARP1 (0.67) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1170818 | 0.83 | CBFB (0.69) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9718865 | 0.82 | GAA (0.65) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29625822 | 0.79 | HPSE (0.65) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28027630 | 0.79 | HPSE (0.65) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14012670 | 0.78 | MGAM (0.65) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9044494 | 0.78 | MGAM (0.71) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8817550 | 0.77 | PARP1 (0.63) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9045175 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4564339 | 0.77 | PARP1 (0.63) | PARP1SMN1; SMN2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |