Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716920 | 0.81 | ALDH1A1 (0.73) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL10752115 | 0.81 | ALDH1A1 (0.73) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7716932 | 0.81 | ALDH1A1 (1.00) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL6816902 | 0.81 | ALDH1A1 (0.72) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL3526801 | 0.80 | KMT2A (0.56) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL30665825 | 0.80 | RECQL (0.55) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL20488395 | 0.80 | RECQL (0.55) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11509602 | 0.79 | KMT2A (0.65) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13219558 | 0.79 | ALDH1A1 (0.81) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7719622 | 0.79 | ALDH1A1 (0.69) | ALDH1A1PKMKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |