Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716920 | 0.85 | ALDH1A1 (0.73) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7716932 | 0.85 | ALDH1A1 (1.00) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL6816902 | 0.84 | ALDH1A1 (0.72) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL13219558 | 0.82 | ALDH1A1 (0.81) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7718005 | 0.81 | ALDH1A1 (0.69) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7719622 | 0.81 | ALDH1A1 (0.69) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7821606 | 0.81 | ALDH1A1 (0.68) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL6538622 | 0.81 | GFER (0.63) | PKMKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7718025 | 0.80 | CYP1A2 (0.68) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL7718019 | 0.80 | KMT2A (0.69) | ALDH1A1PKMKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | disclosed |