Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.69 |
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816902 | 0.88 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7718025 | 0.86 | CYP1A2 (0.68) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7783257 | 0.84 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7821606 | 0.81 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6816232 | 0.81 | MAPT (0.70) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6458171 | 0.80 | KMT2A (0.77) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL13789013 | 0.80 | MAPT (0.69) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7783264 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6814888 | 0.80 | MAPT (0.72) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7716932 | 0.80 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |