Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783257 | 0.90 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7078992 | 0.84 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL7783875 | 0.80 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7718019 | 0.80 | KMT2A (0.69) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6816902 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7783888 | 0.79 | MAPT (0.61) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6811868 | 0.79 | MAPT (0.64) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7718025 | 0.78 | CYP1A2 (0.68) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6814888 | 0.77 | MAPT (0.72) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL10752115 | 0.76 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |