SCHEMBL7718129

SCHEMBL7718129

Nc1ccc(N=Nc2cccc(S(=O)(=O)CCOS(=O)(=O)O)c2)cc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 10/20 0.46
SENP1 Q9P0U3 9/20 0.46
SENP3 Q9H4L4 7/20 0.46
SUMO2 P61956 6/20 0.46
SUMO1 P63165 6/20 0.46
SENP7 Q9BQF6 6/20 0.46
CA12 O43570 4/20 0.41
CA2 P00918 4/20 0.41
CA9 Q16790 4/20 0.41
GLO1 Q04760 4/20 0.40
THRB P10828 1/20 0.39
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749721 0.89 THRB (0.47) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL7717676 0.85 SENP2 (0.43) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL9750184 0.85 SENP2 (0.43) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL7717688 0.83 MEN1 (0.44) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL7720103 0.83 SENP2 (0.47) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL9750422 0.82 SENP2 (0.38) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL9094890 0.82 SENP2 (0.63) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL9094885 0.82 SENP2 (0.63) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL872920 0.82 CTDSP1 (0.40) SENP2SUMO2SUMO1SENP7CA2
SCHEMBL11672358 0.81 CA12 (0.35) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
US-5686642-A Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1997-11-11 US disclosed
US-5597902-A MONOAZO DYES, DISAZO DYES, NAPHTHOL DYES AND TRIAZO DYES FOR SILK, WOOL, LEATHER AND POLYAMIDES OR CELLULOSE BAYER AKTIENGESELLSCHAFT (DE) 1997-01-28 US disclosed
US-5502174-A Reactive dyestuffs based on a substituted barbituric acid BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
US-5093484-A Water soluble; colorfast shades on cotton BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed