Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KLK3 | P07288 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718401 | 0.82 | GAA (0.62) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL7717955 | 0.80 | NPC1 (0.50) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7713539 | 0.77 | MGAM (0.64) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL7719025 | 0.75 | GUSB (0.57) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL7718414 | 0.74 | GUSB (0.60) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL9044504 | 0.74 | GUSB (0.56) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL7716962 | 0.73 | GUSB (0.55) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL5486010 | 0.72 | HTT (0.44) | GAAKMT2AMEN1MAPTPLAU | |
| SCHEMBL2872555 | 0.72 | GUSB (0.68) | GUSBGAAMGAMSIMGAM2 | |
| SCHEMBL31679095 | 0.72 | GUSB (0.68) | GUSBGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376664-B1 | DETECTORS, CATALYST | THE OHIO STATE UNIVERSITY | 2002-04-23 | — | — | US | disclosed |