Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713539 | 0.83 | MGAM (0.64) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL9044494 | 0.80 | MGAM (0.71) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL7719025 | 0.79 | GUSB (0.57) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL9045175 | 0.78 | ALDH1A1 (0.55) | GUSBGAAALDH1A1TDP1AMY1A | |
| SCHEMBL7718414 | 0.78 | GUSB (0.60) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL7129517 | 0.77 | TDP1 (0.43) | GUSBALDH1A1TDP1AMY1AL3MBTL1 | |
| SCHEMBL7716962 | 0.77 | GUSB (0.55) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL14664339 | 0.76 | MMP2 (0.60) | GUSBALDH1A1TDP1AMY1A | |
| SCHEMBL2872555 | 0.76 | GUSB (0.68) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL31679095 | 0.76 | GUSB (0.68) | GUSBMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |