Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555673 | 0.93 | MEN1 (0.41) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL30844063 | 0.83 | MEN1 (0.44) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL1021883 | 0.83 | MEN1 (0.44) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL30392759 | 0.83 | TDP1 (0.41) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL9354521 | 0.83 | TDP1 (0.41) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL31090476 | 0.83 | TDP1 (0.40) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10819483 | 0.80 | ALDH1A1 (0.43) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL11451379 | 0.79 | GPR35 (0.45) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL23888701 | 0.77 | DNMT3B (0.44) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14253769 | 0.77 | MEN1 (0.49) | MAPTMEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112047871-B | Preparation method of indole compound | 南京大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-112047871-A | Preparation method of indole compound | 南京大学 | 2020-12-08 | — | — | CN | disclosed |
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4859551-A | Process for preparing positive and negative images using photohardenable electrostatic master | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0315121-A2 | Process for preparing positive and negative images using photohardenable electrostatic master | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4269933-A | PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4198242-A | Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4131465-A | Radiation sensitive polymeric o-nitrophenyl acetals and element | EASTMAN KODAK COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4086210-A | Radiation sensitive polymeric o-nitrophenyl acetals | EASTMAN KODAK COMPANY (US) | 1978-04-25 | — | — | US | disclosed |