Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 6/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718874 | 1.00 | TERT (0.44) | TERTPTGS1GSTK1ACEOPRM1 | |
| SCHEMBL29790102 | 0.89 | TERT (0.52) | TERTACEMMP2MMECPA1 | |
| SCHEMBL2870304 | 0.89 | TERT (0.52) | TERTACEMMP2MMECPA1 | |
| SCHEMBL2870309 | 0.89 | TERT (0.52) | TERTACEMMP2MMECPA1 | |
| SCHEMBL4088251 | 0.87 | TERT (0.46) | TERTPTGS1GSTK1ACEOPRM1 | |
| SCHEMBL4088259 | 0.87 | TERT (0.46) | TERTPTGS1GSTK1ACEOPRM1 | |
| SCHEMBL30272455 | 0.87 | ACE (0.47) | ACEMMECPA1ACE2ENPEP | |
| SCHEMBL4088242 | 0.82 | TERT (0.42) | TERTOPRM1OPRD1ENPEP | |
| SCHEMBL4088244 | 0.82 | TERT (0.42) | TERTOPRM1OPRD1ENPEP | |
| SCHEMBL4099110 | 0.82 | OPRM1 (0.44) | TERTOPRM1OPRD1OPRK1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379664-B1 | ADMINISTERING HUMAN LENSE THIOTRANSFERASE INHIBITOR POLYPEPTIDE | BOARD OF REGENTS UNIVERSITY OF NEBRASKA-LINCOLN | 2002-04-30 | — | — | US | disclosed |