Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779689 | 0.94 | PTGIR (0.69) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7778654 | 0.85 | PTGIR (0.56) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7718905 | 0.82 | PTGIR (0.65) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7718277 | 0.82 | PTGIR (0.89) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL8078053 | 0.81 | PTGIR (0.43) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7772442 | 0.78 | PTGIR (0.70) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7779787 | 0.78 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7776653 | 0.77 | PTGIR (0.81) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7713237 | 0.76 | PTGIR (0.90) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7778668 | 0.76 | PTGIR (0.47) | PTGIRPTGDRPTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |