Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 8/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718894 | 0.81 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8080971 | 0.79 | PTGIR (0.61) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7779689 | 0.77 | PTGIR (0.69) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL14181690 | 0.75 | ACP3 (0.35) | ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8082944 | 0.73 | PTGIR (0.63) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778654 | 0.73 | PTGIR (0.56) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL8078078 | 0.73 | PTGIR (0.44) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778668 | 0.72 | PTGIR (0.47) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL8068504 | 0.69 | BLM (0.54) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL9017290 | 0.68 | PTGIR (0.44) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |