Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19213219 | 0.84 | TSHR (0.40) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL23600081 | 0.82 | CES2 (0.33) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL8916549 | 0.81 | CES2 (0.30) | CES2LPAR1LPAR3 | |
| SCHEMBL19514067 | 0.79 | — | — | |
| SCHEMBL1221382 | 0.79 | TSHR (0.35) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL19213218 | 0.79 | TSHR (0.35) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL17136266 | 0.79 | TSHR (0.35) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL23395470 | 0.78 | CES2 (0.31) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL18767582 | 0.77 | CES2 (0.33) | CES2TSHRLPAR1LPAR3LMNA | |
| SCHEMBL19213221 | 0.76 | CES2 (0.30) | CES2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6383669-B1 | COMPRISING ZIRCONIUM COMPLEXES WITH A BETA-DIKETONATE AND ALKANOL GROUPS; ELECTRO-CERAMIC DEVICES THEREFROM; USE IN FERRO-ELECTRIC MEMORIES AND INFRA-RED DETECTORS; ZIRCONIUM DIISOPROPOXY BIS(TETRAMETHYLHEPTANEDIOATE) FOR EXAMPLE | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2002-05-07 | — | — | US | disclosed |