Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953069 | 0.77 | ALDH1A1 (0.46) | NOTUMCYP1A2NR4A2LMNATSHR | |
| SCHEMBL4953032 | 0.76 | HTR2C (0.46) | NOTUMCYP1A2LMNATSHRSMN1; SMN2 | |
| SCHEMBL3216695 | 0.76 | HTR2A (0.50) | NOTUMNR3C2SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4071478 | 0.76 | HTR2A (0.51) | NOTUMCYP1A2CYP2A6SLC6A2SLC6A4 | |
| SCHEMBL1092615 | 0.76 | HSD11B1 (0.57) | NOTUMCYP1A2CYP2A6NR4A2HSD11B1 | |
| SCHEMBL5216668 | 0.71 | HTR2C (0.55) | CYP2A6LMNAALDH1A1 | |
| SCHEMBL13209355 | 0.71 | NOTUM (0.50) | NOTUMCYP1A2CYP2A6NR4A2HSD11B1 | |
| SCHEMBL3141727 | 0.71 | NOTUM (0.46) | NOTUMCYP1A2CYP2A6NR4A2HSD11B1 | |
| SCHEMBL28605281 | 0.71 | NOTUM (0.50) | NOTUMCYP1A2CYP2A6NR4A2HSD11B1 | |
| SCHEMBL13311382 | 0.71 | NOTUM (0.50) | NOTUMCYP1A2CYP2A6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376426-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-23 | — | — | US | disclosed |
| WO-2000064889-A1 | HERBICIDAL 3-(HETEROCYCL-1-YL)-URACILS | AMERICAN CYANAMID COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-2000064890-A1 | HERBICIDAL 3-(HETEROCYCL-1-YL)-URACILS | AMERICAN CYANAMID COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |